The Library
Physician-reviewed articles on regenerative medicine, the biological terrain, and the evidence behind surgical alternatives — from Dr. Gurpreet Singh Padda.
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hsCRP and inflammation biomarkers in degenerative joint disease
In 792 MOST cohort participants, hsCRP showed no association with MRI-defined knee inflammation. What a systemic marker can and cannot tell you about a joint.
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Why insurance rarely covers orthobiologic procedures
Coverage is a payer decision, not a clinical finding. What actually drives an orthobiologic denial, who the trials enrolled, and what signing an ABN means.
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Why PRP Results Vary: Platelet Dose and Preparation Quality
PRP is not one product. Platelet dose, leukocyte profile, red cell contamination, and pre-activation change what reaches the joint, and what the studies show.
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When orthobiologics are not the right treatment: how we decide what fits
In a 2026 survey of 357 orthopaedic patients, 66.9% believed orthobiologics could treat cartilage injuries. How we decide when an injection does not fit.
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What happens during a physician-led Clinical Evaluation at Regen.MD
A data review before the session, a 60-minute physician-led root-cause discussion, and a written terrain roadmap naming the bottlenecks and the sequence.
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What Longevity Medicine Actually Includes and What It Does Not
Metabolic and biomarker evaluation with selective orthobiologics and peptide medicine — plus what the trials found, and who those trials screened out.
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Vitamin D Status and Musculoskeletal Healing: What Your Lab Results Mean for Recovery
What a 25-hydroxyvitamin D result means for bone, muscle, and recovery capacity — the adult thresholds in use, and what the 2026 BMJ fracture review actually covers.
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VO2 max as a marker of healthspan: what it measures and how to read the number
The mortality figure quoted for VO2 max is a modelled 3.7% per 1 mL/kg/min, not a measured outcome. What the published cohorts actually show.
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Uric Acid, Joint Pain, and Metabolic Health: What the Data Say and How Regen.MD Takes a Conservative-First Approach
In NHANES 2007-2018, adults in the top quartile of a combined uric acid-inflammation-metabolism score had 2.63x the odds of osteoarthritis.
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Tennis elbow and orthobiologics: what the evidence shows, and which patients the trials left out
PRP results for tennis elbow depend on when you measure and who was enrolled. The trial-by-trial eligibility and exclusion criteria, stated plainly.