Regenerative treatments · PRP, BMAC, peptides

Regenerative Treatments:
PRP, BMAC, Peptides and Nerve Care

Regenerative medicine in St. Louis at Regen.MD runs on four pillars. The first is structural repair with PRP, BMAC and prolotherapy. The second is calming the nerves. The third is metabolic and longevity care, including peptides. The fourth is precise testing.

We are not a menu of shots. We are a system: four Restorative Pillars, put in order by your data. We measure the terrain first. We fix it second. Only then do we rebuild the structure.

“Are you treating the symptom — or the signal?”Watch the 10-minute Clinical Mandate before booking. It will tell you whether this practice is for you.

Watch the Clinical Mandate

Pillar I — Biological Reconstruction

How do PRP, BMAC and prolotherapy rebuild joints?
Structural Restoration

Clinical Brief: Expert Orthobiologic Evaluation & Failed-Treatment Revision →

An orthobiologic injection is not a product. It is the end stage of tissue repair. It is the final order, sent into a body that has been made ready to follow it. Structure is rebuilt here. The reason it failed gets fixed in Pillars II–IV.

Clinical InterventionReconstruction Logic
BMAC / LipogemsAutologous Cellular Therapy
Your own repair cells. Your bone marrow and fat carry them, along with signal proteins. We concentrate them and place them with precision. They are the strongest repair order we can give. So we save them for tissue whose body chemistry has been checked and is ready.
Leukocyte-Rich / Leukocyte-Poor PRPPlatelet Protocols
Repair orders. Platelets send them out. We match the type to the target. Leukocyte-rich PRP gives a tendon a controlled push of inflammation. Leukocyte-poor PRP gives a joint quiet, steady signals.
ProlotherapyDextrose / Hypertonic Solutions
Tighter joints. Loose ligaments make a joint unstable, and an unstable joint grinds itself down. A mild, precise irritant sparks new collagen. That tightens the frame, so the joint no longer has to wear out.
Infrared Laser (Photobiomodulation)Mitochondrial Support
Energy for repair. Certain red and infrared light raises the output of mitochondria, the power plants in your cells. It charges those cell batteries before and after every repair procedure.
Whole-Body Vibrational TherapyPhysical Stimulation
Movement medicine. Controlled shaking drains lymph fluid, builds bone density, and wakes up sleepy muscles. It is for bodies that pain has kept still.
C-arm fluoroscopy procedure suite at Regen.MD, St. Louis
The procedure suite — every needle image-guided
Infrared photobiomodulation laser handpieces at Regen.MD, St. Louis
Infrared photobiomodulation — mitochondrial support

Pillar II — Systemic Regulation

How does calming the nervous system ease chronic pain?
Neurological Modulation

Chronic pain is often an alarm system that has learned the wrong lesson. This pillar resets the nervous system. It quiets nerve circuits stuck in overdrive. It frees trapped nerves. It brings back the calm state the body needs to heal. Nerves stuck in fight-or-flight are a main reason joint and spine procedures fail.

Clinical InterventionRegulation Logic
Stellate Ganglion BlockSympathetic Modulation
A precise numbing reset. It targets the sympathetic chain, the fight-or-flight junction box. It has a proven effect on the body side of PTSD and on complex regional pain. It also helps the nerve-driven states that block bone and joint healing later on.
RF NeurolysisAblation / Neurolysis
A test, not a guess. First, a diagnostic block proves which nerve is sending the pain. Then radio-wave heat stops that nerve signal for 12–24 months. That gives us time to fix the terrain.
Vagal Nerve StimulationNeuromodulation
A master switch. The vagus nerve is the body’s main anti-inflammation circuit. Stimulating it shifts the body from constant alarm into rest and repair. That lowers inflammation through the whole body, from the top down.
HydrodissectionPeripheral Nerve Release
Freeing a trapped nerve. A nerve stuck in scar tissue fires all the time. It is a mechanical problem that looks like a mystery illness. Fluid, guided by ultrasound, frees the nerve without a scalpel.
CryotherapyDesensitization
Cold that calms. Planned cold quiets overactive pain sensors. It also brings a measurable drop in inflammation through the whole body. It turns down the noise in an oversensitive nervous system.
Resetting the nervous system is terrain work — not symptom management

Pillar III — Terrain Optimization

How does metabolic health affect pain and healing?
Metabolic & Longevity

Clinical Brief: The Biological Baseline Program →  ·  Clinical Brief: Peptide Therapy →

The Biological Baseline program. Most chronic pain sits on top of a metabolic fire. That fire is insulin resistance, a leaky gut, and low hormones. This pillar rebuilds the soil so every other treatment holds. It is where most of our patients with failed procedures find out why they failed.

Systemic Inputs

Clinical InterventionOptimization Logic
SIBO Yogurt / Targeted ProbioticsGut Restoration
Gut first. Roughly seventy percent of immune signals start in the gut. Rebuilding gut bacteria with targeted strains restores the barrier. That barrier keeps inflammatory triggers out of the blood.
HBOT — Regenerative ProtocolPhysiological Reset
Oxygen under pressure. Hyperbaric oxygen dissolves oxygen right into the blood plasma. It reaches tissue that damaged small blood vessels cannot feed. It also has a proven effect of calling stem cells into the blood before orthobiologic procedures.
HBOT — Neuro-Recovery ProtocolPTSD / Brain Injury
A separate dosing plan. It raises BDNF, a growth factor for brain cells. It lowers brain inflammation. It is for recovery when the injured organ is the brain itself.
High-Temperature SaunaEnvironmental / Heat
Heat that repairs. Planned heat stress makes heat-shock proteins, the body’s tiny repair crews. It also pushes lymph fluid to move. It is an ancient tool with measurable modern biology.
Personalized Meal ArchitectureNutritional Therapy
Food as a prescription. It is a nutrient plan built from your labs. It removes the foods that feed inflammation. It supplies the building blocks repair needs.
Whole-body red light therapy bed at Regen.MD, St. Louis
Red light therapy — photobiomodulation at systemic scale
Whole-body vibration platforms at Regen.MD, St. Louis
Whole-body vibration — lymphatic and skeletal loading

What is peptide therapy used for? — The Signal Library

Peptides are the native language your cells already speak. We choose them from lab data, never from a menu.

Clinical InterventionSignaling Logic
BPC-157 · TB-500 · Thymosin β-4Repair & Recovery
The workhorse repair stack. It is for joints, tendons, and the gut lining. It is often run alongside Pillar I procedures to stretch out and lock in the repair window.
CJC-1295 · Ipamorelin · Semaglutide · TirzepatideMetabolic & Growth
Hormone tuning. This covers the growth hormone system, plus modern incretin therapy. The goals are fat loss, keeping lean muscle, and breaking down insulin resistance.
MOTS-c · SS-31 · Epitalon · Thymosin α-1Longevity & Mitochondrial
Aimed at aging itself. They target how well mitochondria work, how the immune system is tuned, and cells that have stopped dividing.
Dihexa · Selank · SemaxNeurological / Cognitive
Brain peptides. They feed nerve cells and ease anxiety. They support repair of nerve connections, clear thinking, and stress resilience.
DSIPSleep & Mood
Deep sleep. It restores deep sleep, when growth hormone is released and repair really happens. No body recovers on broken sleep.
GHK-Cu · Matrixyl · SNAP-8Cosmetic / Structural
Skin repair. These are collagen-signal peptides for skin structure. It is the same repair logic, applied to the body’s largest organ.
PT-141Sexual Health
Desire starts in the brain. It works on the melanocortin system for libido and sexual function. It targets the nerve driver, not only blood flow.
KPVInflammatory / Anti-Viral
Gut defense. A short anti-inflammatory peptide drawn to the gut barrier. That barrier is one of the body’s most important borders.

Endocrine & Vitality

Clinical InterventionVitality Logic
Bioidentical HRT / TRTHormone Therapy
Command signals. Hormones run the body. Restoring them, guided by labs, fixes whole-body symptoms like fatigue, mood, body shape, and libido. No local procedure can touch those.
Alma Duo · P-Shot · O-ShotSexual Health
Repair for sexual health. It treats sexual problems with blood flow and tissue repair. It is the orthobiologic logic of Pillar I, applied to erectile and pelvic tissue.
Direct Primary Care ModelConcierge Medicine
Real access. You get open access to your physician and planned prevention. It is medicine at the pace your body needs, not the pace billing allows.

Pillar IV — Data-Driven Truth

What testing comes before regenerative treatment?
Precision Diagnostics

This is the first step before any smart treatment. Nothing in Pillars I–III is used until this pillar has spoken. If you come without data, we start here. If you refuse testing, we decline the case.

Clinical InvestigationTruth Logic
Coronary Artery Calcium ScoreCardiovascular Screening
The honest number. It is a direct picture of the plaque already built up in your heart arteries. No number in heart prevention is more honest. It also shows the history of inflammation in all your blood vessels.
CIMT Carotid Artery EvaluationVascular Age
Vessel age. An ultrasound measures how thick your artery walls are. It shows your blood vessel age next to your real age. Every tissue you want to repair is fed by these vessels.
Stool / SIBO / FSA / DNA PanelsMicrobiome & Permeability
Hidden sources. These tests find a leaky gut, bacterial overgrowth, and food-driven immune triggers. They are the hidden, upstream sources of the inflammation that shows up in your joints.
Cancer / Rare Disease / Food Sensitivity ScreeningProactive Detection
Find it early. Screening is a steady habit, not a reaction to symptoms. The goal is to find disease while the body can still be turned around.
On-site radiography suite at Regen.MD, St. Louis
On-site radiography — measurement before intervention
On-site phlebotomy and laboratory station at Regen.MD, St. Louis
The draw station — where the terrain panel begins
Request Clinical Evaluation Read the Philosophy First
Physician-led · Data-driven · The terrain must be addressed for procedural success

Not sure which guide fits? Take the 60-second candidacy check.


Regenerative treatments · St. Louis

Frequently asked questions

Q1

What types of regenerative medicine are there?

At Regen.MD, regenerative medicine falls into four pillars. Structural repair uses BMAC, Lipogems, PRP and prolotherapy. Calming the nerves uses four tools. They are stellate ganglion blocks, RF neurolysis, vagal nerve stimulation and hydrodissection. Metabolic and longevity care covers gut repair, hyperbaric oxygen, peptides and hormones. Testing comes before all of them. That means tests like a heart calcium score and gut bacteria panels.

Q2

What is BMAC?

BMAC is bone marrow aspirate concentrate. Your bone marrow carries your own repair cells and signal proteins. We concentrate them and place them in the damaged tissue. Every needle is guided by imaging. It is the strongest repair order we can give. So we save it for tissue whose body chemistry has been checked and is ready.

Q3

What is the difference between leukocyte-rich and leukocyte-poor PRP?

Both are platelet-rich plasma, and platelets carry the body’s repair orders. The difference is the white blood cells. Leukocyte-rich PRP keeps them. We use it when a tendon needs a controlled push of inflammation. Leukocyte-poor PRP leaves them out. We use it when a joint needs quiet, steady signals. We match the type to the tissue.

Q4

What is prolotherapy?

Prolotherapy is a shot of dextrose (a sugar water) or a similar strong solution. It acts as a mild, precise irritant. Loose ligaments let a joint move too much, and an unstable joint grinds itself down. The irritation sparks new collagen. That tightens the ligaments, so the joint is steadier and no longer has to wear out.

Q5

What is hydrodissection for a trapped nerve?

A nerve caught in scar tissue can fire all the time. It feels like a mystery pain illness, but it is a mechanical problem. Hydrodissection uses ultrasound to guide fluid around the nerve. The fluid frees it from the tissue holding it, without a scalpel. It is one of the nerve treatments in our pillar for calming the nervous system.