Serving Clayton & Mid-County
Regenerative Medicine in Clayton, MO
Clayton is roughly fifteen minutes from the Regen.MD clinic straight up I-170 — near enough that a full diagnostic workup, a physician-led evaluation and an image-guided procedure can be arranged around a working calendar instead of a medical leave.
Built for the patient who cannot simply stop
Clayton is the seat of St. Louis County government and the county’s corporate and legal center. The people who work here tend to share a particular problem: a knee, a shoulder or a lumbar spine has been declared surgical, and the recovery timeline the surgeon quoted does not fit anywhere in the next twelve months.
Regen.MD exists for that decision point. Not to talk anyone out of an operation that is genuinely indicated, but to establish first — with imaging, diagnostic blocks and measured metabolic chemistry — whether the native joint or disc still has a repair pathway that has never actually been attempted.
Clayton patients also sit minutes from the region’s academic medical district, which means most arrive already deep into a conventional pathway. They have the MRI. They have the surgical opinion. What they usually have not been offered is a read on why the tissue stopped healing in the first place.
What we evaluate
Nearly every case that reaches this clinic has already been through physical therapy, at least one cortisone series and a specialist consultation. We restart the analysis from the biology rather than repeating the same sequence at a higher dose.
- Knee and hip osteoarthritis — including joints labeled bone-on-bone, where replacement has been recommended but the patient wants the native joint evaluated first.
- Shoulder and rotator-cuff degeneration — partial-thickness tears, tendinosis and cuff arthropathy assessed before arthroplasty is scheduled.
- Lumbar and cervical disc disease — degenerative discs, facet-mediated pain and failed-back-surgery syndrome, with the metabolic drivers that keep a disc from repairing.
- Tendon and ligament failure — the elbow, knee and Achilles injuries that quiet down with rest and return within weeks.
- Nerve-mediated and neuropathic pain — burning or radiating symptoms confirmed by diagnostic block before anything is treated.
- Systemic metabolic inflammation — the measurable insulin resistance and inflammatory load working against every condition above.
The interventions available
No single procedure is applied to every case. The evaluation determines which of these image-guided tools the evidence supports for your particular joint, disc or nerve — frequently in combination, and in a deliberate order.
PRP, including intraosseous
Leukocyte-rich and leukocyte-poor preparations, plus intraosseous and subchondral delivery that reaches bone-marrow lesions an intra-articular injection cannot.
BMAC and Lipogems
Autologous bone-marrow concentrate and micro-fragmented adipose tissue where higher-grade repair signaling is warranted.
Intradiscal orthobiologics
PRP or BMAC placed under image guidance into a disc first confirmed as the actual pain generator — the structural path that is not fusion.
Neuromodulation
Stellate ganglion block and radiofrequency neurolysis for sympathetically-maintained and nerve-mediated pain syndromes.
Metabolic and peptide protocols
Hormone, peptide and metabolic prescribing driven by your lab work — the groundwork that determines whether a repair holds.
Adjunctive therapies
Hyperbaric oxygen, photobiomodulation and shockwave, used to raise the tissue’s baseline capacity to respond.
Why chemistry is measured before anything is injected
When an orthobiologic underperforms, the preparation is rarely the reason. Platelets and marrow cells deliver instructions; whether those instructions get carried out depends on the environment receiving them. A body running on insulin resistance, chronic inflammatory load or an unregulated stress response will not execute a repair program regardless of how precisely the needle was placed.
So every evaluation here reads the metabolic and inflammatory panel alongside the imaging. What can be corrected is corrected first, and repeat labs confirm it actually moved before a procedure is scheduled. That ordering — chemistry, then structure — separates relief that fades inside a month from repair that holds.
Getting here from Clayton
From downtown Clayton the clinic is about fifteen minutes north on I-170 to 4477 Woodson Rd, immediately beside St. Louis Lambert International Airport, with parking at the door. Dr. Padda holds hospital staff appointments in both Missouri and Illinois, so continuity is available on the rare occasion a case calls for more than an office-based procedure.
What Clayton patients are usually after
Two things, most often. A forensic explanation of why a previous injection or surgery did not deliver what was promised — and longevity medicine that treats the whole system rather than the loudest joint. Both start from the same data.
Nearby: St. Louis City · Chesterfield · St. Charles · Illinois patients
What the first visit actually is
It is a paid, physician-led Clinical Evaluation with Dr. Padda — not a complimentary qualification call and not a sales appointment. The session runs about an hour and is built entirely on your own data: prior imaging, treatment history and a metabolic panel.
You leave with a written roadmap stating what is driving the problem, which interventions the evidence supports in your case, and the order they should happen in. Because the evaluation depends on reviewing real structural and metabolic data, bring recent imaging and any labs already in hand.
Frequently asked questions
How long does the drive from Clayton take?
About fifteen minutes north on I-170 to 4477 Woodson Rd, Suite 103, in the 63134 ZIP beside Lambert Airport. Parking is at the building. For a fuller picture of what is offered locally, see our orthobiologic approach in St. Louis.
I have had several cortisone injections and they no longer help. What now?
A very common starting point. Cortisone suppresses inflammation without addressing why the tissue is failing, and repeated exposure has been associated with accelerated cartilage loss. We assess the joint and the metabolic terrain together and, where it is appropriate, use orthobiologics intended to repair rather than mask. More detail here: what repeated cortisone does to your cartilage.
Why does Regen.MD test metabolism for a joint problem?
Because the metabolic state determines whether a regenerative procedure can work at all. Correcting the chemistry is not an upsell layered onto the injection — it is the precondition that decides the result. The reasoning is set out in why you cannot out-inject a broken metabolism.
Getting to Regen.MD
4477 Woodson Rd, Suite 103, St. Louis, MO 63134 — directly next to St. Louis Lambert International Airport.
Call (314) 295-3000 · Text (314) 886-5902 · Monday–Friday, 8:00 AM – 5:00 PM
See the clinic map & directions · Meet Dr. Padda & verify credentials
Start with a physician-led evaluation
A structured analysis of your imaging and metabolic data with Dr. Padda — a root-cause session and a written roadmap, not a sales pitch.